Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNT1 | Q5JUK3 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26470386 | 0.82 | ACLY (0.42) | HSD11B1CCND1CCNE1CDK2CDK6 | |
| SCHEMBL2104714 | 0.78 | TP53 (0.44) | HSD11B1 | |
| SCHEMBL25279069 | 0.76 | TP53 (0.38) | CNR1CNR2GAAKCNT1ACLY | |
| SCHEMBL14971519 | 0.75 | MEN1 (0.44) | POLB | |
| SCHEMBL16825250 | 0.75 | POLB (0.38) | CNR1CNR2HSD11B1JAK2JAK1 | |
| SCHEMBL1822000 | 0.75 | CA1 (0.42) | CNR1CNR2HSD11B1JAK2JAK1 | |
| SCHEMBL18711984 | 0.74 | HSD11B1 (0.36) | HSD11B1JAK2JAK1TYK2JAK3 | |
| SCHEMBL12765367 | 0.74 | MAPK1 (0.40) | HSD11B1GAACCND1CCNE1CDK2 | |
| SCHEMBL2424959 | 0.74 | CCNE1 (0.33) | CCND1CCNE1CDK2CDK6 | |
| SCHEMBL2104712 | 0.74 | HSD11B1 (0.35) | CNR1CNR2HSD11B1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830893-A | ROR gamma inhibitor, preparation method and medical application thereof | 成都倍特药业股份有限公司 | 2021-05-25 | — | — | CN | disclosed |