Glycolic Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CA5A	P35218	1/20	0.43

▸	CA5B	Q9Y2D0	1/20	0.43

▸	POLB	P06746	1/20	0.42

▸	APEX1	P27695	1/20	0.38

▸	OR51E2	Q9H255	2/20	0.37

▸	LMNA	P02545	3/20	0.35

▸	LDHA	P00338	1/20	0.35

▸	SRR	Q9GZT4	1/20	0.35

▸	ALKBH5	Q6P6C2	1/20	0.35

▸	SUCNR1	Q9BXA5	1/20	0.35

▸	EGLN1	Q9GZT9	1/20	0.35

▸	TSHR	P16473	3/20	0.33

▸	FFAR3	O14843	1/20	0.33

▸	GLRA1	P23415	1/20	0.33

▸	SLC6A9	P48067	1/20	0.33

▸	TDP1	Q9NUW8	1/20	0.33

▸	CAMK2A	Q9UQM7	1/20	0.33

▸	ALDH1A1	P00352	2/20	0.32

▸	SLC22A6	Q4U2R8	1/20	0.32

▸	GPR84	Q9NQS5	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Glycolic Acid SCHEMBL28580726	1.00	CA5A (0.43)	CA5ACA5BPOLBAPEX1OR51E2
Glycolic Acid SCHEMBL7886469	0.96	CA5A (0.46)	CA5ACA5BPOLBAPEX1OR51E2
Glycolic Acid SCHEMBL11271690	0.93	CA5A (0.43)	CA5ACA5BPOLBAPEX1OR51E2
Glycolic Acid SCHEMBL31071036	0.84	OR51E2 (0.47)	OR51E2LMNALDHASRRALKBH5
Glycolic Acid SCHEMBL4143655	0.84	OR51E2 (0.47)	OR51E2LMNALDHASRRALKBH5
Glycolic Acid SCHEMBL1628476	0.84	—	—
Glycolic Acid SCHEMBL59682	0.84	—	—
Sulfamate SCHEMBL27632035	0.83	TSHR (0.53)	CA5ACA5BPOLBAPEX1OR51E2
Sulfamate SCHEMBL10910798	0.83	TSHR (0.53)	CA5ACA5BPOLBAPEX1OR51E2
Glycolic Acid SCHEMBL900919	0.83	LDHA (0.41)	POLBAPEX1OR51E2LMNALDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115645610-A	Nerve conduit, preparation method and application thereof	深圳先进技术研究院	2023-01-31	—	—	CN	claimed
CN-115645610-A	Nerve conduit, preparation method and application thereof	深圳先进技术研究院	2023-01-31	—	—	CN	disclosed
CN-112718028-B	Light-operated liquid drop motion material and preparation method and application thereof	深圳先进技术研究院	2022-11-01	—	—	CN	disclosed
CN-113616859-A	Antibacterial lubricating coating and preparation method and application thereof	深圳先进技术研究院	2021-11-09	—	—	CN	disclosed
CN-112870391-A	Ferroelectric antibacterial material and preparation method and application thereof	深圳先进技术研究院	2021-06-01	—	—	CN	disclosed
CN-112718028-A	Light-operated liquid drop motion material and preparation method and application thereof	深圳先进技术研究院	2021-04-30	—	—	CN	disclosed