Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 6/20 | 0.59 |
| ▸ | HTR2C | P28335 | 5/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4875370 | 0.95 | HTR6 (0.70) | HTR6HTR2AHTR2CCNR1DRD2 | |
| Hydrochloric Acid SCHEMBL5130227 | 0.93 | HTR6 (0.68) | HTR6HTR2AHTR2CCNR1DRD2 | |
| SCHEMBL22221978 | 0.88 | HTR6 (0.61) | HTR6HTR2AHTR2CCNR1DRD2 | |
| SCHEMBL14074161 | 0.83 | HTR2A (0.63) | HTR6HTR2AHTR2CCNR1DRD2 | |
| SCHEMBL6476562 | 0.81 | HTR6 (0.55) | HTR6HTR2AHTR2CCNR1DRD2 | |
| SCHEMBL22221974 | 0.81 | HTR6 (0.55) | HTR6HTR2AHTR2CCNR1DRD2 | |
| SCHEMBL2789743 | 0.79 | HTR6 (0.71) | HTR6HTR2AHTR2CCNR1DRD2 | |
| SCHEMBL7613059 | 0.79 | KDM4E (0.64) | HTR6HTR2AHTR2CKDM4EALDH1A1 | |
| Cyanide SCHEMBL28575462 | 0.79 | ALDH1A1 (0.63) | HTR6KDM4EALDH1A1MAPT | |
| SCHEMBL11354470 | 0.79 | HTR6 (0.55) | HTR6HTR2AHTR2CDRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876488-B | Spiro indoline derivative and preparation method and application thereof | 苏州大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-112876488-A | Spiro indoline derivative and preparation method and application thereof | 苏州大学 | 2021-06-01 | — | — | CN | disclosed |