Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862714 | 0.93 | TSHR (0.46) | CCR1TSHRMAPK1P2RX7SMN1; SMN2 | |
| SCHEMBL2852241 | 0.92 | MAPK1 (0.53) | CCR1TSHRMAPK1P2RX7SMN1; SMN2 | |
| SCHEMBL2859307 | 0.91 | TSHR (0.46) | CCR1TSHRMAPK1P2RX7SMN1; SMN2 | |
| SCHEMBL2856625 | 0.90 | TSHR (0.48) | CCR1TSHRMAPK1P2RX7SMN1; SMN2 | |
| SCHEMBL2853334 | 0.89 | CCR1 (0.47) | CCR1MAPK1PTGESP2RX7TRPC3 | |
| SCHEMBL2856212 | 0.88 | CCR1 (0.47) | CCR1TSHRMAPK1P2RX7SMN1; SMN2 | |
| SCHEMBL2857994 | 0.87 | MTOR (0.46) | CCR1P2RX7 | |
| SCHEMBL2856556 | 0.86 | CCR1 (0.54) | CCR1 | |
| SCHEMBL2859091 | 0.86 | CCR1 (0.46) | CCR1MAPK1P2RX7 | |
| SCHEMBL2852454 | 0.85 | KDM4E (0.48) | CCR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |