Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMO | Q99835 | 7/20 | 0.45 |
| ▸ | CCR1 | P32246 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862714 | 0.93 | TSHR (0.46) | MAPK1P2RX7TSHRSMOCCR1 | |
| SCHEMBL2858209 | 0.92 | CCR1 (0.48) | MAPK1P2RX7TSHRCCR1SMN1; SMN2 | |
| SCHEMBL2859307 | 0.91 | TSHR (0.46) | MAPK1P2RX7TSHRCCR1SMN1; SMN2 | |
| SCHEMBL2855493 | 0.91 | P2RX7 (0.48) | MAPK1P2RX7SMOCCR1 | |
| SCHEMBL2856625 | 0.90 | TSHR (0.48) | MAPK1P2RX7TSHRSMOCCR1 | |
| SCHEMBL2850425 | 0.89 | P2RX7 (0.49) | MAPK1P2RX7SMOCCR1 | |
| SCHEMBL2856212 | 0.88 | CCR1 (0.47) | MAPK1P2RX7TSHRCCR1SMN1; SMN2 | |
| SCHEMBL2859091 | 0.86 | CCR1 (0.46) | MAPK1P2RX7SMOCCR1 | |
| SCHEMBL2863210 | 0.85 | CCR1 (0.50) | MAPK1P2RX7SMOCCR1 | |
| SCHEMBL2855710 | 0.85 | LMNA (0.46) | MAPK1P2RX7SMOCCR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |