Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862714 | 0.92 | TSHR (0.46) | TSHRP2RX7CCR1SMN1; SMN2MAPT | |
| SCHEMBL2852241 | 0.91 | MAPK1 (0.53) | TSHRP2RX7CCR1SMN1; SMN2MAPK1 | |
| SCHEMBL2858209 | 0.91 | CCR1 (0.48) | TSHRP2RX7CCR1SMN1; SMN2MAPK1 | |
| SCHEMBL2860826 | 0.90 | KDM4E (0.43) | P2RX7KDM4EALDH1A1CCR1PPARG | |
| SCHEMBL2856356 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1CCR1NPSR1SMN1; SMN2 | |
| SCHEMBL2856625 | 0.89 | TSHR (0.48) | TSHRP2RX7CCR1PPARGNPSR1 | |
| SCHEMBL2861243 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1CCR1NPSR1SMN1; SMN2 | |
| SCHEMBL2856212 | 0.87 | CCR1 (0.47) | TSHRP2RX7CCR1NPSR1SMN1; SMN2 | |
| SCHEMBL2854847 | 0.86 | ALDH1A1 (0.48) | P2RX7KDM4EALDH1A1CCR1SMN1; SMN2 | |
| SCHEMBL2852454 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1CCR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |