SCHEMBL28583121 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	2/20	0.48

▸	KMT2A	Q03164	2/20	0.48

▸	PTPRA	P18433	1/20	0.43

▸	NPSR1	Q6W5P4	1/20	0.42

▸	ADAMTS5	Q9UNA0	1/20	0.41

▸	ALKBH2	Q6NS38	1/20	0.41

▸	ALKBH5	Q6P6C2	1/20	0.41

▸	ALKBH3	Q96Q83	1/20	0.41

▸	FTO	Q9C0B1	1/20	0.41

▸	HSD17B10	Q99714	1/20	0.40

▸	GAA	P10253	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16058321	0.80	ADAMTS5 (0.52)	MEN1KMT2APTPRAADAMTS5HSD17B10
SCHEMBL21885547	0.80	ADAMTS5 (0.52)	MEN1KMT2APTPRAADAMTS5HSD17B10
SCHEMBL32668282	0.79	MEN1 (0.54)	MEN1KMT2ANPSR1
Bromide SCHEMBL29831731	0.79	ADAMTS5 (0.51)	MEN1KMT2APTPRAADAMTS5HSD17B10
SCHEMBL5693309	0.73	KMT2A (0.54)	MEN1KMT2ANPSR1
SCHEMBL29182363	0.72	MEN1 (0.46)	MEN1KMT2ANPSR1
SCHEMBL25227152	0.72	KMT2A (0.56)	MEN1KMT2ANPSR1
SCHEMBL25277181	0.72	KMT2A (0.56)	MEN1KMT2ANPSR1
SCHEMBL21837591	0.72	MEN1 (0.46)	MEN1KMT2ANPSR1
SCHEMBL21837408	0.72	MEN1 (0.46)	MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-107709301-B	Pyrazole derivative or pharmacologically acceptable salt thereof	橘生药品工业株式会社	2021-06-22	—	—	CN	disclosed