Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575832 | 0.87 | LMNA (0.48) | LMNACYP2D6CYP2C19POLBCYP2C9 | |
| SCHEMBL21594849 | 0.77 | S1PR1 (0.41) | S1PR1RAB9AHDAC1ALDH1A1CHKA | |
| SCHEMBL7283544 | 0.77 | F10 (0.51) | — | |
| SCHEMBL21594891 | 0.76 | CHKA (0.50) | KMT2AS1PR1RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL3582057 | 0.75 | KMT2A (0.61) | LMNACYP2D6CYP2C19POLBCYP2C9 | |
| SCHEMBL3560004 | 0.73 | RAB9A (0.56) | LMNAKMT2ARAB9AHDAC1HTT | |
| SCHEMBL12451876 | 0.72 | HDAC1 (0.66) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL12038114 | 0.72 | S1PR1 (0.78) | LMNACYP2D6CYP2C19POLBCYP2C9 | |
| SCHEMBL2964066 | 0.72 | DRD2 (0.57) | LMNACYP2D6CYP2C19POLBCYP2C9 | |
| SCHEMBL12275459 | 0.71 | FFAR4 (0.48) | CYP2D6CYP2C19POLBCYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112888696-B | Exonuclease inhibitors and methods of use thereof | 德琪医疗有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-112888696-A | Exonucleotidase inhibitors and methods of use thereof | 卡利泰拉生物科技公司 | 2021-06-01 | — | — | CN | disclosed |