Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 8/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583365 | 1.00 | NR1D1 (0.39) | NR1D1SMYD3PPARGMAPK11MAPK14 | |
| SCHEMBL21822431 | 0.88 | ST14 (0.42) | SMYD3F2EPHX2 | |
| SCHEMBL25017655 | 0.82 | F10 (0.43) | SMYD3MAPK11MAPK14F2 | |
| SCHEMBL28578356 | 0.82 | F10 (0.43) | SMYD3MAPK11MAPK14F2 | |
| SCHEMBL28580154 | 0.76 | F10 (0.44) | SMYD3F2 | |
| SCHEMBL28580156 | 0.76 | F10 (0.44) | SMYD3F2 | |
| SCHEMBL25015957 | 0.76 | F2 (0.45) | SMYD3F2 | |
| SCHEMBL25016807 | 0.75 | CNR2 (0.41) | SMYD3F2 | |
| SCHEMBL31689670 | 0.74 | F10 (0.45) | SMYD3MAPK11MAPK14F2NOD2 | |
| SCHEMBL28572148 | 0.74 | F10 (0.45) | SMYD3MAPK11MAPK14F2NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |