Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28584199 | 1.00 | MAPT (0.51) | MAPTGFERLMNAALDH1A1HPGD | |
| SCHEMBL28593831 | 0.85 | GPR119 (0.49) | MAPTGFERLMNAALDH1A1HPGD | |
| SCHEMBL28593829 | 0.85 | GPR119 (0.49) | MAPTGFERLMNAALDH1A1HPGD | |
| SCHEMBL17746120 | 0.81 | MAPT (0.47) | MAPTGFERLMNAMEN1KMT2A | |
| SCHEMBL27152523 | 0.81 | HRH3 (0.47) | MAPTGFERLMNACHRM4SMN1; SMN2 | |
| SCHEMBL18244948 | 0.81 | ALDH1A1 (0.46) | MAPTGFERLMNAALDH1A1HPGD | |
| SCHEMBL6904992 | 0.81 | MAPK1 (0.55) | MAPTGFERLMNASMN1; SMN2SLC6A7 | |
| SCHEMBL103471 | 0.80 | ALDH1A1 (0.43) | MAPTGFERLMNAALDH1A1HPGD | |
| SCHEMBL3596565 | 0.80 | KDM4E (0.57) | MAPTALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL3596569 | 0.80 | KDM4E (0.57) | MAPTALDH1A1HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |