Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28584601 | 1.00 | RORC (0.48) | RORCPPARDPPARACA1CA2 | |
| SCHEMBL23632476 | 0.90 | FFAR1 (0.46) | RORCPPARDPPARACA1CA2 | |
| SCHEMBL23632478 | 0.90 | FFAR1 (0.46) | RORCPPARDPPARACA1CA2 | |
| SCHEMBL28600738 | 0.87 | RORC (0.45) | RORCHIF1AEPAS1 | |
| SCHEMBL28600736 | 0.87 | RORC (0.45) | RORCHIF1AEPAS1 | |
| SCHEMBL28585300 | 0.86 | RORC (0.47) | RORC | |
| SCHEMBL23636751 | 0.85 | RORC (0.54) | RORC | |
| SCHEMBL30842592 | 0.84 | RORC (0.45) | RORCHIF1AEPAS1 | |
| SCHEMBL23636942 | 0.84 | HDAC1 (0.60) | RORC | |
| SCHEMBL21619696 | 0.83 | RORC (0.51) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |