Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600736 | 1.00 | RORC (0.45) | RORCHIF1AEPAS1 | |
| SCHEMBL28585300 | 0.90 | RORC (0.47) | RORC | |
| SCHEMBL28584604 | 0.87 | RORC (0.48) | RORCHIF1AEPAS1 | |
| SCHEMBL28584601 | 0.87 | RORC (0.48) | RORCHIF1AEPAS1 | |
| SCHEMBL30842592 | 0.80 | RORC (0.45) | RORCHIF1AEPAS1 | |
| SCHEMBL23636942 | 0.80 | HDAC1 (0.60) | RORC | |
| SCHEMBL23636983 | 0.80 | RORC (0.45) | RORC | |
| SCHEMBL23632216 | 0.79 | RORC (0.38) | RORC | |
| SCHEMBL23632212 | 0.79 | RORC (0.38) | RORC | |
| SCHEMBL23636751 | 0.79 | RORC (0.54) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |