Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858479 | 1.00 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4659375 | 0.83 | MTNR1A (0.46) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1942392 | 0.83 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4659374 | 0.83 | MTNR1A (0.46) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7584602 | 0.83 | MTNR1A (0.46) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL76489 | 0.79 | ALDH1A1 (0.67) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28820697 | 0.79 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9750180 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9750183 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9750169 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318156-B1 | Novel asymmetric phosphine ligand | TAKASAGO PERFUMERY CO LTD (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1279660-B1 | Process for producing an optically active amide from an alpha, beta-unsaturated amide derivative in the presence of an optically active transition metal complex containing a phosphine-phosphorane compound and rhodium | TAKASAGO PERFUMERY CO LTD (JP) | 2008-12-17 | — | — | EP | disclosed |
| EP-1318155-B1 | Novel asymmetric phosphine ligand | TAKASAGO PERFUMERY CO LTD (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-6855847-B2 | Process for producing optically active amide from α β- unsaturated amide derivative in the presence of transition metal complex containing phosphine-phosphorane compound and transition metal | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-02-15 | — | — | US | disclosed |
| US-6730629-B2 | HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-05-04 | — | — | US | disclosed |
| US-6624320-B2 | Phosphorane compound hydrogenation catalyts; stereospecific; catalyst selectivity | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-09-23 | — | — | US | disclosed |
| US-20030144138-A1 | NOVEL ASYMMETRIC PHOSPHINE LIGAND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| US-20030139285-A1 | Novel asymmetric phosphine ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-07-24 | — | — | US | disclosed |
| US-20030120067-A1 | Process for producing optically active amide from alpha beta- unsaturated amide derivative in the presence of transition metal complex containing phosphine-phosphorane compound and transition metal | TAKASAGO INTERNATIONAL CORPORATION | 2003-06-26 | — | — | US | disclosed |
| EP-1318156-A1 | Novel asymmetric phosphine ligand | Takasago International Corporation (JP) | 2003-06-11 | — | — | EP | disclosed |
| EP-1318155-A1 | Novel asymmetric phosphine ligand | Takasago International Corporation (JP) | 2003-06-11 | — | — | EP | disclosed |
| EP-1279660-A1 | Process for producing an optically active amide from an alpha, beta-unsaturated amide derivative in the presence of a transition metal complex containing a phosphine-phosphorane compound and a transition metal | Takasago International Corporation (JP) | 2003-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120067-A1 | Process for producing optically active amide from alpha beta- unsaturated amide derivative in the presence of transition metal complex containing phosphine-phosphorane compound and transition metal | PHOSPHO1, NAAA, DEGS1 | ALDH1A1 1510/4885NPC1 3840/4885RAB9A 1220/4885 |
| US-20030144138-A1 | NOVEL ASYMMETRIC PHOSPHINE LIGAND | PHOSPHO1, PLCG2, PLCB3 | ALDH1A1 2360/4885NPC1 4581/4885RAB9A 641/4885 |
| US-20030139285-A1 | Novel asymmetric phosphine ligand | PHOSPHO1, PAPSS1, PPM1F | ALDH1A1 2528/4885NPC1 3780/4885RAB9A 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.