Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PNP | P00491 | 6/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591797 | 0.82 | PNP (0.52) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL6268785 | 0.71 | PNP (0.55) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL8905863 | 0.70 | PNP (0.51) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL8630516 | 0.69 | MEN1 (0.59) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL5503608 | 0.67 | HPRT1 (0.56) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL15643286 | 0.67 | MEN1 (0.58) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL8190548 | 0.67 | PNP (0.65) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL9417217 | 0.67 | MEN1 (0.45) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL28591909 | 0.66 | MEN1 (0.47) | MEN1KMT2APNPBLMUSP2 | |
| SCHEMBL19258972 | 0.66 | MEN1 (0.47) | MEN1KMT2APNPBLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112367988-A | Compositions and methods relating to ethoxydihydroxybutanone derivatives | 芝加哥大学 | 2021-02-12 | — | — | CN | disclosed |