Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TK1 | P04183 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586056 | 0.82 | MEN1 (0.44) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL6265339 | 0.78 | TK1 (0.62) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL6268785 | 0.78 | PNP (0.55) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL10917250 | 0.77 | TK1 (0.65) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL455494 | 0.76 | PNP (0.64) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL27667781 | 0.76 | TK1 (0.60) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL874736 | 0.75 | PNP (0.64) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL6266779 | 0.75 | TK1 (0.58) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL6268087 | 0.75 | TK1 (0.58) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL6265535 | 0.74 | TK1 (0.61) | PNPBLMHBBUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112367988-A | Compositions and methods relating to ethoxydihydroxybutanone derivatives | 芝加哥大学 | 2021-02-12 | — | — | CN | disclosed |