Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220154 | 0.88 | PTPN1 (0.51) | SMN1; SMN2MAPK1PTPN1L3MBTL1TSHR | |
| SCHEMBL3671710 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPK1PTPN1L3MBTL1TSHR | |
| SCHEMBL7567008 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1PTPN1L3MBTL1TSHR | |
| SCHEMBL7942502 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1PTPN1L3MBTL1TSHR | |
| SCHEMBL3711484 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1PTPN1L3MBTL1TSHR | |
| Dimethoxymethane SCHEMBL27820464 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPK1L3MBTL1TSHRPOLB | |
| SCHEMBL6550273 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1PTPN1L3MBTL1ALDH1A1 | |
| SCHEMBL6550190 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1PTPN1L3MBTL1TSHR | |
| SCHEMBL29955198 | 0.83 | ENPP2 (0.53) | SMN1; SMN2MAPK1PTPN1L3MBTL1TSHR | |
| SCHEMBL10971500 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPK1L3MBTL1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109152762-B | Compound for promoting osteoblast differentiation and inhibiting adipocyte differentiation, preparation method and application thereof | 成均生物株式会社 | 2021-07-13 | — | — | CN | disclosed |