SCHEMBL6550273

SCHEMBL6550273

COCOc1c(CCl)cccc1OC

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
BCHE P06276 6/20 0.42
PTPN1 P18031 1/20 0.42
ABCB1 P08183 3/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
HTR1A P08908 2/20 0.39
ADRA1D P25100 2/20 0.39
ADRA1A P35348 2/20 0.39
ADRA1B P35368 2/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3072812 0.85 SMN1; SMN2 (0.55) SMN1; SMN2BCHEHTR1AADRA1DADRA1A
SCHEMBL2500056 0.83 SMN1; SMN2 (0.50) SMN1; SMN2ABCB1ABCG2MAPK1ALDH1A1
SCHEMBL3066643 0.83 SMN1; SMN2 (0.62) SMN1; SMN2HTR1AADRA1DADRA1AADRA1B
SCHEMBL28586196 0.83 SMN1; SMN2 (0.65) SMN1; SMN2PTPN1HTR1AADRA1DADRA1A
SCHEMBL6550190 0.83 SMN1; SMN2 (0.47) SMN1; SMN2BCHEPTPN1ABCB1ABCG2
SCHEMBL4101732 0.81 ABCB1 (0.56) SMN1; SMN2BCHEABCB1ABCG2HTR1A
SCHEMBL18608388 0.80 SMN1; SMN2 (0.58) SMN1; SMN2BCHEHTR1AADRA1DADRA1A
SCHEMBL8964423 0.79 BCHE (0.68) BCHEKDM4EL3MBTL1
SCHEMBL6472775 0.78 L3MBTL1 (0.39) PTPN1ABCB1HTR1AALDH1A1KDM4E
SCHEMBL4113689 0.78 SMN1; SMN2 (0.54) SMN1; SMN2BCHEHTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1172916-C Oxime O-ether compounds and agricultural and horticultural fungicides �ձ�������ʽ���� 2004-10-27 CN disclosed
EP-1236717-B1 OXIME O-ETHER COMPOUNDS AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE NIPPON SODA CO (JP) 2004-02-04 EP disclosed
US-6589967-B1 Fungicide for agricultural and horticultural use comprising the compound as the active ingredient. agricultural plant protection chemicals have been used for controlling plant diseases. NIPPON SODA CO. LTD. (JP) 2003-07-08 US disclosed
CN-1387515-A Oxime O-ether compounds and fungicides for agricultural and horticultural use NIPPON SODA CO (JP) 2002-12-25 CN disclosed
EP-1236717-A1 OXIME O-ETHER COMPOUNDS AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE NIPPON SODA CO., LTD. (JP) 2002-09-04 EP disclosed