Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 5/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20732114 | 1.00 | PTGS2 (0.41) | PTGS2MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL30060129 | 1.00 | PTGS2 (0.41) | PTGS2MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL31582778 | 0.84 | L3MBTL1 (0.42) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20722890 | 0.81 | USP2 (0.45) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20722892 | 0.81 | USP2 (0.45) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL29223124 | 0.78 | PTGS2 (0.41) | PTGS2MAPTALDH1A1KIF11 | |
| SCHEMBL3751401 | 0.75 | HDAC8 (0.56) | HDAC8 | |
| SCHEMBL2895605 | 0.75 | HDAC8 (0.56) | HDAC8 | |
| SCHEMBL2895608 | 0.75 | HDAC8 (0.56) | HDAC8 | |
| Hydrochloric Acid SCHEMBL6560412 | 0.74 | PTGS2 (0.41) | PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |