SCHEMBL28586426

SCHEMBL28586426

N#CN1CCCC1n1cnc(-c2cccc(-c3cncnc3)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28586992 0.90 USP30 (0.53) USP30
SCHEMBL28603773 0.89 USP30 (0.50) USP30
SCHEMBL28604258 0.88 USP30 (0.55) USP30
SCHEMBL28608678 0.85 USP30 (0.56) USP30
SCHEMBL28586850 0.84 USP30 (0.56) USP30
SCHEMBL28582103 0.83 USP30 (0.55) USP30
SCHEMBL28594572 0.83 USP30 (0.59) USP30
SCHEMBL28592396 0.82 DRD2 (0.45) USP30
SCHEMBL28594554 0.81 USP30 (0.58) USP30
SCHEMBL28592627 0.79 USP30 (0.48) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884068-B 1-cyano-pyrrolidine derivatives as DUB inhibitors 特殊治疗有限公司 2021-02-26 — — CN disclosed
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