Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 15/20 | 0.53 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586426 | 0.90 | USP30 (0.53) | USP30 | |
| SCHEMBL28603773 | 0.88 | USP30 (0.50) | USP30UCHL1 | |
| SCHEMBL28586850 | 0.88 | USP30 (0.56) | USP30 | |
| SCHEMBL28604258 | 0.87 | USP30 (0.55) | USP30 | |
| SCHEMBL28608678 | 0.84 | USP30 (0.56) | USP30 | |
| SCHEMBL28594572 | 0.84 | USP30 (0.59) | USP30UCHL1NAAA | |
| SCHEMBL28582103 | 0.82 | USP30 (0.55) | USP30 | |
| SCHEMBL28594554 | 0.82 | USP30 (0.58) | USP30UCHL1 | |
| SCHEMBL28592396 | 0.81 | DRD2 (0.45) | USP30UCHL1NAAA | |
| SCHEMBL28592627 | 0.81 | USP30 (0.48) | USP30UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884068-B | 1-cyano-pyrrolidine derivatives as DUB inhibitors | 特殊治疗有限公司 | 2021-02-26 | — | — | CN | disclosed |