Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | TEK | Q02763 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594554 | 0.88 | USP30 (0.58) | USP30UCHL1 | |
| SCHEMBL28586850 | 0.88 | USP30 (0.56) | USP30 | |
| SCHEMBL28603773 | 0.84 | USP30 (0.50) | USP30UCHL1 | |
| SCHEMBL28586992 | 0.84 | USP30 (0.53) | USP30NAAAUCHL1 | |
| SCHEMBL28608678 | 0.83 | USP30 (0.56) | USP30 | |
| SCHEMBL28586426 | 0.83 | USP30 (0.53) | USP30 | |
| SCHEMBL28604258 | 0.81 | USP30 (0.55) | USP30 | |
| SCHEMBL28592400 | 0.81 | USP30 (0.59) | USP30NAAAUCHL1 | |
| SCHEMBL28917627 | 0.80 | USP30 (0.56) | USP30KCNH2 | |
| SCHEMBL28592396 | 0.80 | DRD2 (0.45) | USP30NAAAUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884068-B | 1-cyano-pyrrolidine derivatives as DUB inhibitors | 特殊治疗有限公司 | 2021-02-26 | — | — | CN | disclosed |