Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28584793 | 0.79 | HDAC4 (0.36) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| SCHEMBL28600791 | 0.79 | HDAC4 (0.36) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| SCHEMBL28578099 | 0.79 | HDAC4 (0.36) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| SCHEMBL28577978 | 0.76 | HDAC4 (0.33) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| SCHEMBL27108161 | 0.75 | RXRA (0.41) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| SCHEMBL8211755 | 0.72 | TYR (0.52) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| SCHEMBL374780 | 0.72 | HDAC4 (0.56) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| Water SCHEMBL9322811 | 0.70 | HDAC4 (0.54) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| SCHEMBL11036540 | 0.70 | HDAC4 (0.54) | HDAC4HDAC8TP53SMN1; SMN2KDM4E | |
| Benzene SCHEMBL7084450 | 0.70 | HDAC4 (0.54) | HDAC4HDAC8TP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092761-B | Halogenated 1,2, 3-triazole carbene as well as preparation method and application thereof | 中国人民大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-110092761-A | Halogenated 1,2,3- triazole Cabbeen and its preparation method and application | 中国人民大学 | 2019-08-06 | — | — | CN | disclosed |