SCHEMBL28587223

SCHEMBL28587223

Nc1cc(C(=O)C(=O)c2ccccc2)c(N)c(N)c1N

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 11/20 0.52
CES1 P23141 9/20 0.52
MAPT P10636 3/20 0.44
GAA P10253 1/20 0.44
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
THRB P10828 1/20 0.39
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
MCL1 Q07820 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RAB9A P51151 1/20 0.39
PBRM1 Q86U86 1/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686613 0.83 MAPT (0.60) MAPTGAAPOLBKDM4EMEN1
Hydrochloric Acid SCHEMBL5169493 0.81 MAPT (0.58) MAPTGAAPOLBKDM4EMEN1
SCHEMBL19253345 0.79 MAPT (0.39) MAPTGAAPOLBKDM4EMEN1
SCHEMBL6691083 0.76 MAPT (0.67) CES2CES1MAPTGAAPOLB
SCHEMBL1885623 0.76 MAPT (0.55) CES2CES1MAPTGAAPOLB
Benzil SCHEMBL3796381 0.75 MAPT (0.64) CES2CES1MAPTGAAPOLB
SCHEMBL15846543 0.74 CES2 (0.52) CES2CES1MAPTGAAPOLB
Hydrochloric Acid SCHEMBL27739689 0.74 MAPT (0.53) CES2CES1MAPTGAAPOLB
SCHEMBL28110230 0.74 MAPT (0.53) CES2CES1MAPTGAAPOLB
Hydrochloric Acid SCHEMBL8607225 0.74 CES2 (0.47) CES2CES1MAPTGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979946-A Benzimidazole anion exchange membrane and preparation method thereof 广州费舍尔人工智能技术有限公司 2021-06-18 CN disclosed