SCHEMBL28587252

SCHEMBL28587252

O=C1C(=O)c2ccc(-c3ccccc3)cc2-c2cc(-c3ccccc3)ccc21

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.91
NPC1 O15118 3/20 0.91
MAPT P10636 3/20 0.91
KMT2A Q03164 3/20 0.91
SMN1; SMN2 Q16637 3/20 0.91
APAF1 O14727 2/20 0.91
LMNA P02545 2/20 0.91
THRB P10828 2/20 0.91
HTT P42858 2/20 0.91
RAB9A P51151 2/20 0.91
GALK1 P51570 2/20 0.91
BLM P54132 2/20 0.91
NPSR1 Q6W5P4 2/20 0.91
XBP1 P17861 1/20 0.91
PTBP1 P26599 1/20 0.91
SMAD3 P84022 1/20 0.91
ATM Q13315 1/20 0.91
L3MBTL1 Q9Y468 1/20 0.91
MAOA P21397 3/20 0.55
MAOB P27338 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29679055 1.00 MEN1 (0.91) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL15383587 0.96 MEN1 (1.00) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL30719688 0.95 NPC1 (0.83) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL18073335 0.95 NPC1 (0.83) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL28198235 0.91 MEN1 (0.92) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL978978 0.91 NPC1 (0.92) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL4410719 0.91 MEN1 (0.76) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL15383588 0.91 MEN1 (0.83) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL57813 0.88 NPC1 (0.80) MEN1NPC1MAPTKMT2ASMN1; SMN2
SCHEMBL21993324 0.88 NPC1 (0.80) MEN1NPC1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271247-A AIE type I photosensitizer, nanoparticle, preparation method and application thereof in antibiosis 广州医科大学 2024-07-02 CN claimed
CN-118271247-A AIE type I photosensitizer, nanoparticle, preparation method and application thereof in antibiosis 广州医科大学 2024-07-02 CN disclosed
CN-113121511-B Phenanthroimidazole electroluminescent material with circular polarization luminescence, preparation method and application thereof 华南理工大学 2022-05-24 CN disclosed
CN-113121511-A Phenanthroimidazole electroluminescent material with circular polarization luminescence, preparation method and application thereof 华南理工大学 2021-07-16 CN disclosed