Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587269 | 1.00 | KMT2A (0.38) | KMT2AALDH1A1MEN1TDP1HSP90AA1 | |
| SCHEMBL28568650 | 0.78 | NFE2L2 (0.37) | TDP1MAPTKDM4EKCNH2SMN1; SMN2 | |
| SCHEMBL28568651 | 0.78 | NFE2L2 (0.37) | TDP1MAPTKDM4EKCNH2SMN1; SMN2 | |
| SCHEMBL7736581 | 0.77 | KMT2A (0.61) | KMT2AALDH1A1MEN1TDP1HSP90AA1 | |
| SCHEMBL28568741 | 0.75 | CYP1A1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL28568739 | 0.75 | CYP1A1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL28575488 | 0.69 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL28575487 | 0.69 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL9571098 | 0.69 | TSHR (0.42) | ALDH1A1LMNANFKB1DRD3TAAR1 | |
| SCHEMBL7024779 | 0.68 | NFE2L2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109021003-B | Preparation method of vinyl silicon/germanium/stannane derivative | 华侨大学 | 2021-06-01 | — | — | CN | disclosed |