Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568651 | 1.00 | NFE2L2 (0.37) | NFE2L2KCNH2MAT2ATDP1KDM4E | |
| SCHEMBL13100027 | 0.77 | ERN1 (0.38) | NFE2L2KCNH2MAT2ATDP1CYP2C9 | |
| SCHEMBL28568739 | 0.75 | CYP1A1 (0.40) | NFE2L2KDM4ELMNAMAPTCYP1A2 | |
| SCHEMBL28568741 | 0.75 | CYP1A1 (0.40) | NFE2L2KDM4ELMNAMAPTCYP1A2 | |
| SCHEMBL28575487 | 0.69 | ALDH1A1 (0.40) | KDM4ENPC1MAPTRAB9ACYP1A2 | |
| SCHEMBL28575488 | 0.69 | ALDH1A1 (0.40) | KDM4ENPC1MAPTRAB9ACYP1A2 | |
| SCHEMBL713563 | 0.69 | CES2 (0.38) | — | |
| SCHEMBL7024779 | 0.68 | NFE2L2 (0.30) | NFE2L2 | |
| SCHEMBL8932025 | 0.68 | ACHE (0.43) | NFE2L2NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28217811 | 0.66 | ACHE (0.42) | NFE2L2NPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109021003-B | Preparation method of vinyl silicon/germanium/stannane derivative | 华侨大学 | 2021-06-01 | — | — | CN | disclosed |