Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 6/20 | 0.97 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.80 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TTR | P02766 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzarone SCHEMBL555497 | 0.99 | EYA3 (1.00) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| Benzarone SCHEMBL29576057 | 0.99 | EYA3 (1.00) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL1287913 | 0.88 | EYA3 (0.81) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL11840583 | 0.87 | EYA3 (0.85) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL12286119 | 0.87 | EYA3 (0.79) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL28101771 | 0.87 | EYA3 (0.79) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL27935343 | 0.86 | EYA3 (0.77) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL1287385 | 0.86 | EYA3 (0.77) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL1287970 | 0.85 | EYA3 (1.00) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 | |
| SCHEMBL1287413 | 0.84 | SLC22A12 (1.00) | EYA3SLC22A12CYP2C9PTPN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113173898-A | Synthesis method of benzbromarone key intermediate | 内蒙古康普药业有限公司 | 2021-07-27 | — | — | CN | disclosed |