Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327651 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MEN1POLBKMT2AMAPT | |
| SCHEMBL28587504 | 0.73 | CA1 (0.43) | ALDH1A1MEN1POLBKMT2AMAPT | |
| SCHEMBL28370186 | 0.73 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28596272 | 0.66 | MEN1 (0.40) | ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL28593612 | 0.66 | ALDH1A1 (0.41) | ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL9748745 | 0.65 | — | — | |
| SCHEMBL32679653 | 0.64 | ALDH1A1 (0.41) | ALDH1A1MEN1POLBKMT2AMAPT | |
| SCHEMBL28414581 | 0.63 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AMAPT | |
| SCHEMBL25920572 | 0.63 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AMAPT | |
| SCHEMBL28581855 | 0.62 | CA2 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111961060-B | Preparation method of spiroheterocyclic 2, 3-dihydrobenzofuran compound with optical activity | 遵义医科大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111961060-A | Preparation method of spiroheterocyclic 2, 3-dihydrobenzofuran compound with optical activity | 遵义医科大学 | 2020-11-20 | — | — | CN | disclosed |