Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534377 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1POLBCASP3 | |
| SCHEMBL28593612 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1POLBCHRM5 | |
| SCHEMBL29785238 | 0.78 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1POLBCHRM5 | |
| SCHEMBL2816698 | 0.78 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1POLBCHRM5 | |
| SCHEMBL28428472 | 0.77 | HSPA1A (0.39) | MEN1KMT2AALDH1A1POLBCHRM5 | |
| SCHEMBL11265954 | 0.73 | TTR (0.58) | MEN1KMT2AALDH1A1TRPA1CASP3 | |
| SCHEMBL20534453 | 0.68 | PARK7 (0.36) | MEN1KMT2AALDH1A1CASP3BRD4 | |
| SCHEMBL20534614 | 0.68 | CA1 (0.44) | CHRM5TRPA1CASP3BRD4CASP1 | |
| SCHEMBL5001267 | 0.67 | CHRM5 (0.60) | MEN1KMT2AALDH1A1POLBCHRM5 | |
| SCHEMBL5502497 | 0.66 | MEN1 (0.49) | MEN1KMT2AALDH1A1POLBCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111961060-B | Preparation method of spiroheterocyclic 2, 3-dihydrobenzofuran compound with optical activity | 遵义医科大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111961060-A | Preparation method of spiroheterocyclic 2, 3-dihydrobenzofuran compound with optical activity | 遵义医科大学 | 2020-11-20 | — | — | CN | disclosed |