Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872754 | 0.98 | ZDHHC7 (0.41) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL27889133 | 0.98 | ZDHHC7 (0.41) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL28718237 | 0.92 | KMT2A (0.39) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL30475458 | 0.88 | CA2 (0.54) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL14593930 | 0.88 | KMT2A (0.39) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL27933679 | 0.87 | CA2 (0.53) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL11617086 | 0.85 | ZDHHC7 (0.35) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL24515841 | 0.85 | ALDH1A1 (0.37) | CA1CA2CA12CA14MEN1 | |
| SCHEMBL5812132 | 0.85 | CA1 (0.52) | CA1CA2ZDHHC7CTSK | |
| SCHEMBL28722541 | 0.85 | LTA4H (0.46) | CA1MEN1GAAKMT2ANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107873023-B | 3-alkyl-4-amido-bicyclo [4, 5, 0] hydroxamic acids as HDAC inhibitors | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |