Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608511 | 0.81 | RECQL (0.58) | CA1CA2CA9RECQLCA12 | |
| SCHEMBL691846 | 0.81 | CA1 (0.61) | CA1CA2CA9CA12MPO | |
| SCHEMBL28583909 | 0.76 | HDAC1 (0.72) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL2678949 | 0.76 | MPO (0.80) | CA1CA2CA9RECQLMPO | |
| SCHEMBL11217374 | 0.76 | PLK1 (0.72) | CA1CA2MPOCYP3A4KDM5A | |
| SCHEMBL343630 | 0.76 | MPO (0.80) | CA1CA2CA9RECQLMPO | |
| SCHEMBL11139882 | 0.74 | MPO (0.64) | CA1CA2CA9MPOCYP3A4 | |
| SCHEMBL2836138 | 0.74 | CYP3A4 (0.53) | CA1CA2CA9MPOCYP3A4 | |
| SCHEMBL28188923 | 0.73 | MPO (0.76) | CA1CA2CA9RECQLMPO | |
| SCHEMBL4616920 | 0.73 | CA2 (1.00) | CA1CA2CA9CA12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922362-B | 1,3, 4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社钟根堂 | 2021-06-15 | — | — | CN | disclosed |