Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804763 | 0.85 | PLA2G10 (0.48) | RECQLCA2PLA2G10PLA2G2ACA1 | |
| SCHEMBL28587714 | 0.81 | CA1 (0.58) | RECQLCA2CA1CA12CA9 | |
| SCHEMBL2720492 | 0.80 | PLA2G10 (0.44) | RECQLCA2PLA2G10PLA2G2ACA1 | |
| SCHEMBL24495645 | 0.80 | CA2 (0.55) | RECQLCA2PLA2G10PLA2G2ACA1 | |
| SCHEMBL507412 | 0.79 | EPHX2 (0.44) | CA2PLA2G10PLA2G2ACA1CA12 | |
| SCHEMBL507413 | 0.76 | DPP4 (0.43) | CA2PLA2G10PLA2G2APARP10KMT2A | |
| SCHEMBL2633786 | 0.75 | PLA2G10 (0.55) | RECQLCA2PLA2G10PLA2G2ACA1 | |
| SCHEMBL2861358 | 0.75 | PLA2G10 (0.55) | RECQLCA2PLA2G10PLA2G2ACA1 | |
| SCHEMBL11166463 | 0.75 | RECQL (0.96) | RECQLCA2CA1CA12CA9 | |
| SCHEMBL6608518 | 0.75 | RECQL (0.67) | RECQLCA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368327-B1 | BENZO THIADIAZINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-10-20 | — | — | EP | claimed |