Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314324 | 0.82 | RECQL (0.61) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL3412403 | 0.82 | RECQL (0.61) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL314323 | 0.82 | RECQL (0.61) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL9718496 | 0.81 | CYP1B1 (0.69) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL9718492 | 0.81 | CYP1B1 (0.69) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL11694299 | 0.81 | CYP1B1 (0.73) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL11694297 | 0.81 | CYP1B1 (0.73) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL28900947 | 0.79 | ALDH1A1 (0.65) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL21065368 | 0.79 | ALDH1A1 (0.56) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 | |
| SCHEMBL710586 | 0.79 | RECQL (0.68) | MAPTSMN1; SMN2NPC1RAB9ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003173-B | Carbazole-based two-photon polar fluorescent probe and preparation method and application thereof | 安徽大学 | 2021-05-04 | — | — | CN | disclosed |