SCHEMBL21065368

SCHEMBL21065368

CC=CC(=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
SRD5A2 P31213 1/20 0.54
RECQL P46063 2/20 0.53
MAPT P10636 4/20 0.52
LMNA P02545 4/20 0.52
CYP1B1 Q16678 2/20 0.52
PLIN1 O60240 2/20 0.52
PLIN5 Q00G26 2/20 0.52
ABHD5 Q8WTS1 2/20 0.52
BCHE P06276 1/20 0.52
TNFRSF1A P19438 1/20 0.52
ACHE P22303 1/20 0.52
MAOB P27338 1/20 0.52
HPGD P15428 4/20 0.50
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
AKT1 P31749 2/20 0.49
CYP3A4 P08684 1/20 0.49
ELANE P08246 1/20 0.48
TDP1 Q9NUW8 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3412403 0.92 RECQL (0.61) ALDH1A1RECQLMAPTLMNACYP1B1
SCHEMBL314324 0.92 RECQL (0.61) ALDH1A1RECQLMAPTLMNACYP1B1
SCHEMBL314323 0.92 RECQL (0.61) ALDH1A1RECQLMAPTLMNACYP1B1
SCHEMBL20272963 0.82 ALDH1A1 (0.54) ALDH1A1SRD5A2MAPTLMNAHPGD
SCHEMBL28835815 0.81 AKR1C3 (0.57) ALDH1A1RECQLMAPTELANETDP1
SCHEMBL27947435 0.79 TRPA1 (0.58) ALDH1A1RECQLMAPTLMNACYP1B1
SCHEMBL27947433 0.79 TRPA1 (0.58) ALDH1A1RECQLMAPTLMNACYP1B1
SCHEMBL28588201 0.79 MAPT (0.53) ALDH1A1RECQLMAPTLMNACYP1B1
SCHEMBL22572689 0.78 RECQL (0.52) ALDH1A1RECQLMAPTLMNACYP1B1
SCHEMBL22129150 0.78 ELANE (0.66) ALDH1A1SRD5A2NPC1ELANEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10927064-B2 Process for the manufacturing of a compound comprising a (meth)acryloyl group 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-02-23 US disclosed
US-20200369590-A1 PROCESS FOR THE MANUFACTURING OF A COMPOUND COMPRISING A (METH)ACRYLOYL GROUP 3M INNOVATIVE PROPERTIES COMPANY 2020-11-26 US disclosed
EP-3502090-B1 PROCESS FOR THE MANUFACTURING OF A COMPOUND COMPRISING A (METH)ACRYLOYL GROUP 3M INNOVATIVE PROPERTIES CO (US) 2020-08-19 EP disclosed
EP-3502090-A1 PROCESS FOR THE MANUFACTURING OF A COMPOUND COMPRISING A (METH)ACRYLOYL GROUP 3M Innovative Properties Company (US) 2019-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927064-B2 Process for the manufacturing of a compound comprising a (meth)acryloyl group ADH5, ALKBH3, METTL3 ALDH1A1 138/4885SRD5A2 3755/4885RECQL 3334/4885
US-20200369590-A1 PROCESS FOR THE MANUFACTURING OF A COMPOUND COMPRISING A (METH)ACRYLOYL GROUP ADH5, ALKBH3, METTL3 ALDH1A1 138/4885SRD5A2 3755/4885RECQL 3334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.