Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 9/20 | 0.48 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598763 | 0.92 | SLC6A5 (0.49) | SLC6A5DRD4SSTR5F10TEAD1 | |
| SCHEMBL21822299 | 0.91 | DRD4 (0.50) | SLC6A5DRD4F10TEAD1DRD2 | |
| SCHEMBL21822512 | 0.91 | DRD4 (0.50) | SLC6A5DRD4F10TEAD1DRD2 | |
| SCHEMBL21822147 | 0.85 | CCR9 (0.45) | SLC6A5DRD4F10TEAD1DRD2 | |
| SCHEMBL21822290 | 0.84 | DRD4 (0.51) | SLC6A5DRD4F10TEAD1DRD2 | |
| SCHEMBL28579689 | 0.84 | DRD4 (0.46) | SLC6A5DRD4F10HTTF2 | |
| SCHEMBL21822925 | 0.78 | CCR9 (0.49) | SLC6A5DRD4F10TEAD1 | |
| SCHEMBL21822510 | 0.78 | F10 (0.47) | SLC6A5DRD4F10F2PRSS1 | |
| SCHEMBL28572149 | 0.77 | F10 (0.45) | DRD4F10F2PRSS1 | |
| SCHEMBL28572148 | 0.77 | F10 (0.45) | DRD4F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |