Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 6/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822334 | 0.90 | DRD4 (0.49) | DRD4F10SLC6A5EPHX2F2 | |
| SCHEMBL28598763 | 0.88 | SLC6A5 (0.49) | DRD4F10SLC6A5F2PRSS1 | |
| SCHEMBL28588320 | 0.84 | SLC6A5 (0.48) | DRD4F10SLC6A5F2PRSS1 | |
| SCHEMBL28588235 | 0.80 | SMN1; SMN2 (0.46) | F10F2PRSS1MAPTHTT | |
| SCHEMBL28572148 | 0.79 | F10 (0.45) | DRD4F10F2PRSS1ST14 | |
| SCHEMBL28572149 | 0.79 | F10 (0.45) | DRD4F10F2PRSS1ST14 | |
| SCHEMBL28573728 | 0.79 | F2 (0.50) | F10F2PRSS1ST14MAPT | |
| SCHEMBL28573604 | 0.79 | SMYD3 (0.47) | DRD4F10F2PRSS1ST14 | |
| SCHEMBL28573606 | 0.79 | SMYD3 (0.47) | DRD4F10F2PRSS1ST14 | |
| SCHEMBL28573730 | 0.79 | F2 (0.50) | F10F2PRSS1ST14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |