Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.55 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HCK | P08631 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785338 | 0.82 | SRC (0.56) | SRCHCKPIM1ABL1NPC1 | |
| SCHEMBL2832666 | 0.73 | SRC (0.59) | SRCHTR2CHCKPIM1ABL1 | |
| SCHEMBL2807570 | 0.73 | PIK3CA (0.56) | SRCHTR2CABL1NPC1RAB9A | |
| SCHEMBL2810178 | 0.71 | GAA (0.56) | SRCHTR2CABL1NPC1RAB9A | |
| SCHEMBL17726066 | 0.71 | SRC (1.00) | SRCHCKPIM1ABL1 | |
| SCHEMBL2786942 | 0.71 | HRH4 (0.54) | SRCHTR2CALDH1A1ABL1MAPT | |
| SCHEMBL2856614 | 0.71 | PDE5A (0.55) | SRCALDH1A1MAPTHPGDTP53 | |
| SCHEMBL2882852 | 0.70 | HTR2C (0.61) | SRCHTR2CABL1 | |
| SCHEMBL2856457 | 0.69 | PIK3CA (0.52) | SRCHTR2CALDH1A1ABL1NPC1 | |
| SCHEMBL2786916 | 0.69 | PIK3CA (0.51) | SRCHTR2CALDH1A1ABL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |