Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 12/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785338 | 0.89 | SRC (0.56) | GAAKMT2AMEN1ABL1BCR | |
| SCHEMBL2855842 | 0.81 | HTR2C (0.48) | HTR2CABL1BCRNPC1RAB9A | |
| SCHEMBL2832666 | 0.77 | SRC (0.59) | HTR2CABL1MAPTSRC | |
| SCHEMBL2864782 | 0.77 | MEN1 (0.53) | HTR2CKMT2AMEN1ABL1BCR | |
| SCHEMBL2852113 | 0.75 | MAPT (0.53) | GAAKMT2AMEN1ABL1NPC1 | |
| SCHEMBL2804510 | 0.75 | NPC1 (0.47) | HTR2CKMT2AMEN1ABL1BCR | |
| SCHEMBL31194465 | 0.75 | PDE2A (0.60) | HTR2CABL1SRC | |
| SCHEMBL2786539 | 0.74 | PDE1A (0.42) | GAAKMT2AABL1BCRNPC1 | |
| SCHEMBL29582070 | 0.74 | GAA (0.80) | GAAHTR2CKMT2AMEN1MAPT | |
| SCHEMBL22806016 | 0.74 | GAA (0.80) | GAAHTR2CKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |