Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HCK | P08631 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810178 | 0.89 | GAA (0.56) | SRCGAAKMT2AABL1MEN1 | |
| SCHEMBL2858840 | 0.82 | SRC (0.55) | SRCHCKPIM1ABL1NPC1 | |
| SCHEMBL2852113 | 0.81 | MAPT (0.53) | SRCGAAKMT2AHCKPIM1 | |
| SCHEMBL2804593 | 0.80 | ALDH1A1 (0.54) | SRCGAAKMT2AHCKPIM1 | |
| SCHEMBL2786539 | 0.75 | PDE1A (0.42) | GAAKMT2AABL1CYP1A2CYP3A4 | |
| SCHEMBL2195032 | 0.75 | HTR2C (0.57) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL25876283 | 0.74 | PDE1A (0.44) | NPC1RAB9A | |
| SCHEMBL2832666 | 0.74 | SRC (0.59) | SRCHCKPIM1ABL1 | |
| SCHEMBL22587402 | 0.73 | GAA (0.48) | SRCGAAKMT2AABL1MEN1 | |
| SCHEMBL2856614 | 0.73 | PDE5A (0.55) | SRCKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |