Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 3/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483246 | 1.00 | ATR (0.41) | ATRALDH1A1LMNAPOLBRXRA | |
| SCHEMBL29921383 | 0.84 | CYP4F2 (0.43) | ATRALDH1A1LMNAPOLBRXRA | |
| SCHEMBL28575619 | 0.84 | CYP4F2 (0.43) | ATRALDH1A1LMNAPOLBRXRA | |
| SCHEMBL30483254 | 0.83 | ATR (0.42) | ATRALDH1A1LMNAPOLBRXRA | |
| SCHEMBL28588706 | 0.83 | ATR (0.42) | ATRALDH1A1LMNAPOLBRXRA | |
| SCHEMBL29147744 | 0.79 | CHRM2 (0.34) | ATRALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL30633955 | 0.79 | CHRM2 (0.34) | ATRALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL18399275 | 0.76 | RXRA (0.48) | ATRALDH1A1LMNAPOLBRXRA | |
| SCHEMBL19617703 | 0.75 | RXRA (0.41) | ATRALDH1A1LMNAPOLBRXRA | |
| SCHEMBL30064825 | 0.75 | RXRA (0.41) | ATRALDH1A1LMNAPOLBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004252-B | Aryl imidazole derivative and application thereof | 江苏先声药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-113004252-A | Aryl imidazole derivative and application thereof | 江苏先声药业有限公司 | 2021-06-22 | — | — | CN | disclosed |