Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591940 | 0.88 | EDNRA (0.53) | EDNRA | |
| SCHEMBL28591865 | 0.83 | SLC6A2 (0.50) | CYP19A1GID4 | |
| SCHEMBL11548037 | 0.82 | — | — | |
| SCHEMBL28585810 | 0.81 | GID4 (0.42) | GID4EDNRBEDNRA | |
| SCHEMBL28590553 | 0.80 | ALDH1A1 (0.40) | DDB1CRBN | |
| SCHEMBL6944891 | 0.80 | — | — | |
| SCHEMBL28599087 | 0.78 | GID4 (0.41) | CYP19A1GID4 | |
| SCHEMBL28917266 | 0.78 | DRD2 (0.41) | GID4EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL7322861 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7322867 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794308-B | 1,2,3, 4-tetrahydronaphthalene compound and preparation method and application thereof | 北京大学深圳研究生院 | 2021-07-20 | — | — | CN | disclosed |