Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724405 | 0.89 | JAK2 (0.30) | JAK2JAK1TYK2JAK3HTR3A | |
| SCHEMBL21724622 | 0.81 | JAK1 (0.38) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL21724911 | 0.76 | TLR7 (0.46) | — | |
| SCHEMBL30777927 | 0.65 | JAK1 (0.40) | JAK2JAK1TYK2JAK3ALDH1A1 | |
| SCHEMBL21733006 | 0.63 | TLR7 (0.38) | — | |
| SCHEMBL21566202 | 0.63 | ALDH1A1 (0.36) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL19895857 | 0.61 | TSHR (0.42) | L3MBTL1 | |
| SCHEMBL21724518 | 0.60 | JAK1 (0.53) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL2657770 | 0.56 | TSHR (0.71) | LMNAALDH1A1AR | |
| SCHEMBL22469745 | 0.55 | TSHR (0.62) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113038989-A | Imidazo [4,5-C ] quinoline-derived NLRP3 modulators | 先天肿瘤免疫公司 | 2021-06-25 | — | — | CN | disclosed |