⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618538 | 1.00 | — | — | |
| SCHEMBL1372187 | 1.00 | — | — | |
| SCHEMBL2231883 | 0.87 | KMT2A (0.61) | — | |
| SCHEMBL2231885 | 0.87 | KMT2A (0.61) | — | |
| SCHEMBL27920233 | 0.85 | ALOX15 (0.45) | — | |
| SCHEMBL27920265 | 0.83 | ALOX15 (0.43) | — | |
| SCHEMBL23581537 | 0.83 | ALOX15 (0.59) | — | |
| SCHEMBL29120332 | 0.79 | — | — | |
| SCHEMBL5855330 | 0.78 | ALOX15 (0.34) | — | |
| SCHEMBL5855322 | 0.78 | ALOX15 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211242-B1 | PROSTAGLANDIN DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2010-01-13 | — | — | EP | disclosed |
| US-6822112-B1 | PROSTAGLANDIN D2 AGONISTS; KIDNEY, CARDIOVASCULAR, AND SLEEP DISORDERS; ANTIISCHEMIC AND HYPOTENSIVE AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-6740772-B1 | Prostaglandin derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-05-25 | — | — | US | disclosed |
| CN-1368959-A | Prostaglandin derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |