Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.55 |
| ▸ | SQLE | Q14534 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231885 | 1.00 | KMT2A (0.61) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL1372187 | 0.87 | — | — | |
| SCHEMBL618538 | 0.87 | — | — | |
| SCHEMBL2859080 | 0.87 | — | — | |
| SCHEMBL28472717 | 0.83 | KMT2A (0.67) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL2496380 | 0.82 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL2495543 | 0.82 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8978471 | 0.82 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL871914 | 0.82 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL2495546 | 0.82 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572938-B2 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2009-08-11 | — | — | US | claimed |
| US-20040171516-A1 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2004-09-02 | — | — | US | claimed |
| EP-1262473-A1 | Precursors for fragrant ketones and fragrant aldehydes | Givaudan SA (CH) | 2002-12-04 | — | — | EP | claimed |
| US-20220403289-A1 | ALPHA-HYDROXYISOBUTYRIC ACID ESTER COMPOUND AND FRAGRANCE COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-12-22 | — | — | US | disclosed |
| CN-114867829-A | Alpha-hydroxyisobutyrate compound and perfume composition | 三菱瓦斯化学株式会社 | 2022-08-05 | — | — | CN | disclosed |
| WO-2021132214-A1 | α-HYDROXYISOBUTYRIC ACID ESTER COMPOUND AND FRAGRANCE COMPOSITION | 三菱瓦斯化学株式会社 | 2021-07-01 | — | — | WO | disclosed |
| US-7977315-B2 | prenylation enzyme inhibitors such as 5,9,13-trimethyl-2-nitrotetradeca-2,8,12-triene, used as anticarcinogenic or antitumor agents | ARIZONA BIOMEDICAL RESEARCH COMMISSION (US) | 2011-07-12 | — | — | US | disclosed |
| US-7572938-B2 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2009-08-11 | — | — | US | disclosed |
| US-20080113919-A1 | Conjugated Nitro Alkene Anticancer Agents Based on Isoprenoid Metabolism | ARIZONA BIOMEDICAL RESEARCH COMMISSION (US) | 2008-05-15 | — | — | US | disclosed |
| US-7312191-B2 | Conjugated nitro alkene anticancer agents based on isoprenoid metabolism | ARIZONA BIOMEDICAL RESEARCH COMMISSION (US) | 2007-12-25 | — | — | US | disclosed |
| WO-2005016864-A1 | CONJUGATED NITRO ALKENE ANTICANCER AGENTS BASED ON ISOPRENOID METABOLISM | THE ARIZONA DISEASE CONTROL RESEARCH COMMISSION (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050026812-A1 | Conjugated nitro alkene anticancer agents based on isoprenoid metabolism | ARIZONA DISEASE CONTROL RESEARCH COMMISSION (US) | 2005-02-03 | — | — | US | disclosed |
| US-20040171516-A1 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2004-09-02 | — | — | US | disclosed |
| EP-1390337-A1 | PRECURSORS FOR KETONES AND ALDEHYDES | Givaudan SA (CH) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002096850-A1 | PRECURSORS FOR KETONES AND ALDEHYDES | GIVAUDAN SA (CH) | 2002-12-05 | — | — | WO | disclosed |
| EP-1262473-A1 | Precursors for fragrant ketones and fragrant aldehydes | Givaudan SA (CH) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220403289-A1 | ALPHA-HYDROXYISOBUTYRIC ACID ESTER COMPOUND AND FRAGRANCE COMPOSITION | CYP8B1, HCAR1, GABRB1 | KMT2A 2989/4885MAPT 2615/4885MEN1 1266/4885 |
| US-20080113919-A1 | Conjugated Nitro Alkene Anticancer Agents Based on Isoprenoid Metabolism | RHOA, ARHGDIB, RHOT2 | KMT2A 4031/4885MAPT 4449/4885MEN1 2286/4885 |
| US-20050026812-A1 | Conjugated nitro alkene anticancer agents based on isoprenoid metabolism | RHOA, ARHGDIB, RHOT2 | KMT2A 4031/4885MAPT 4449/4885MEN1 2286/4885 |
| US-20040171516-A1 | Precursors for ketones and aldehydes | PDK3, PDK4, AKR1C4 | KMT2A 2984/4885MAPT 3633/4885MEN1 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.