Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30331291 | 1.00 | MAPT (0.56) | MAPTHSD17B10MAPK1ALOX15KDM4E | |
| SCHEMBL3879139 | 0.87 | GAA (0.55) | MAPTHSD17B10MAPK1ALOX15KDM4E | |
| SCHEMBL9172083 | 0.85 | MAPT (0.56) | MAPTHSD17B10MAPK1ALOX15KDM4E | |
| SCHEMBL27508628 | 0.85 | GAA (0.53) | MAPTHSD17B10MAPK1ALOX15KDM4E | |
| SCHEMBL29215682 | 0.85 | ALDH1A1 (0.54) | MAPTHSD17B10MAPK1ALOX15KDM4E | |
| SCHEMBL11211367 | 0.85 | MAPT (0.56) | MAPTHSD17B10MAPK1ALOX15KDM4E | |
| SCHEMBL1758260 | 0.84 | KMT2A (0.51) | MAPTHSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL30996458 | 0.83 | POLB (0.55) | MAPTHSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL29215536 | 0.83 | POLB (0.55) | MAPTHSD17B10ALOX15KDM4EMEN1 | |
| SCHEMBL29366285 | 0.82 | HDAC1 (0.66) | MAPTHSD17B10MAPK1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179000-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2025-06-05 | — | — | US | disclosed |
| EP-4452918-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023122276-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-06-29 | — | — | WO | disclosed |
| US-9394555-B2 | Compositions comprising a polypeptide having cellulolytic enhancing activity and a dioxy compound and uses thereof | NOVOZYMES, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20130157317-A1 | Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Dioxy Compound And Uses Thereof | NOVOZYMES, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-7713449-B2 | Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell | TORAY INDUSTRIES, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| CN-100364160-C | Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell | TORAY INDUSTRIES (JP) | 2008-01-23 | — | — | CN | disclosed |
| US-20060180796-A1 | Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell | TORAY INDUSTRIES, INC. (JP) | 2006-08-17 | — | — | US | disclosed |
| EP-1619735-A1 | POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL | TORAY INDUSTRIES, INC. (JP) | 2006-01-25 | — | — | EP | disclosed |
| US-20050288346-A1 | Acetophenone potentiators of metabotropic glutamate receptors | MERCK & CO., INC. | 2005-12-29 | — | — | US | disclosed |
| EP-0846673-A1 | High molecular weight dibenzoylresorcinol UV absorbers | GENERAL ELECTRIC COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5763674-A | High molecular weight dibenzoylresorcinol UV absorbers | GENERAL ELECTRIC COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0240723-B1 | UV-LIGHT STABILIZER COMPOSITION COMPRISING CYCLIC ALIPHATIC EPOXY, UV SCREENER, AND POLYALKYLDIPIPERIDINE (HALS) COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5026751-A | For a polyphenylene ether, 2-hydroxybenzophenone | GENERAL ELECTRIC COMPANY (US) | 1991-06-25 | — | — | US | disclosed |
| US-4843116-A | SHAPED PLASTICS | GENERAL ELECTRIC COMPANY (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0240723-A2 | UV-light stabilizer composition comprising cyclic aliphatic epoxy, UV screener, and polyalkyldipiperidine (HALS) compounds | GENERAL ELECTRIC COMPANY (US) | 1987-10-14 | — | — | EP | disclosed |
| US-4349607-A | UV Stabilizers, coating compositions and composite structures obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4349607-A | UV Stabilizers, coating compositions and composite structures obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4288631-A | 3-ALKYLHYDROXYBENZOPHENONES | GENERAL ELECTRIC COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
| US-4288631-A | 3-ALKYLHYDROXYBENZOPHENONES | GENERAL ELECTRIC COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179000-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF | GRM3, GRM2, GRM1 | MAPT 1240/4885HSD17B10 3733/4885MAPK1 1549/4885 |
| US-20050288346-A1 | Acetophenone potentiators of metabotropic glutamate receptors | GRM2, GRM1, GRIK2 | MAPT 1622/4885HSD17B10 372/4885MAPK1 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.