Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | GPR6 | P46095 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854321 | 0.91 | MAPT (0.53) | MAPTCCR1PTPN1GPR6POLB | |
| SCHEMBL2854177 | 0.88 | CCR1 (0.58) | MAPTCCR1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL2852358 | 0.88 | ALDH1A1 (0.48) | MAPTCCR1PTPN1GPR6POLB | |
| SCHEMBL2854614 | 0.85 | MAPT (0.49) | MAPTCCR1GPR6POLBSMN1; SMN2 | |
| SCHEMBL2857887 | 0.83 | HSP90AA1 (0.52) | MAPTCCR1PTPN1GPR6SMN1; SMN2 | |
| SCHEMBL2852994 | 0.83 | ALDH1A1 (0.56) | MAPTCCR1GPR6POLBSMN1; SMN2 | |
| SCHEMBL2854414 | 0.82 | MAPT (0.53) | MAPTCCR1GPR6POLBSMN1; SMN2 | |
| SCHEMBL2862087 | 0.80 | MAPT (0.51) | MAPTCCR1GPR6POLBSMN1; SMN2 | |
| SCHEMBL2856206 | 0.80 | ALDH1A1 (0.48) | MAPTCCR1PTPN1GPR6POLB | |
| SCHEMBL10366449 | 0.79 | MAPT (0.53) | MAPTCCR1GPR6POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |