Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854321 | 0.90 | MAPT (0.53) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2850211 | 0.88 | MAPT (0.49) | MAPTPOLBSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL2854456 | 0.86 | MEN1 (0.47) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2854614 | 0.82 | MAPT (0.49) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2854667 | 0.82 | ALDH1A1 (0.55) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2854177 | 0.81 | CCR1 (0.58) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2854414 | 0.81 | MAPT (0.53) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2859264 | 0.80 | MAPT (0.46) | MAPTPOLBSMN1; SMN2GRIA2ALDH1A1 | |
| SCHEMBL2853014 | 0.79 | KDM4E (0.60) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10364986 | 0.79 | MAPT (0.65) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |