Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12183 | 0.98 | MAOB (0.44) | MAOBMAOAPTPN1CHRNB2CHRNA4 | |
| Formic Acid SCHEMBL28395993 | 0.86 | MAOB (0.49) | MAOBMAOAPTPN1CA2 | |
| Methylchromone SCHEMBL29387804 | 0.80 | MAOB (0.56) | MAOBMAOAPTPN1SMN1; SMN2 | |
| Methylchromone SCHEMBL25934 | 0.80 | MAOB (0.56) | MAOBMAOAPTPN1SMN1; SMN2 | |
| Methylchromone SCHEMBL29160528 | 0.79 | MAOB (0.55) | MAOBMAOAPTPN1SMN1; SMN2 | |
| Ethoxycarbonyl Group SCHEMBL29184215 | 0.77 | MAOB (0.47) | MAOBMAOAPTPN1CA2SMN1; SMN2 | |
| SCHEMBL23652461 | 0.73 | PFKFB3 (0.54) | PTPN1KCNA3 | |
| SCHEMBL1133152 | 0.73 | CHRM2 (0.41) | MAOBMAOAPTPN1CHRNB2CHRNA4 | |
| SCHEMBL2490828 | 0.72 | CHRM2 (0.50) | MAOBMAOAPTPN1CA2SMN1; SMN2 | |
| SCHEMBL24428634 | 0.72 | KCNA3 (0.38) | MAOBCYP1A2SMN1; SMN2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384753-B | Synthetic method of 2-phenyl-3-methylbenzofuran compound | 沈阳药科大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-109384753-A | A kind of synthetic method of 2- phenyl -3- methyl-benzofuran compounds | 沈阳药科大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-109384753-A | A kind of synthetic method of 2- phenyl -3- methyl-benzofuran compounds | 沈阳药科大学 | 2019-02-26 | — | — | CN | disclosed |