Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858311 | 0.91 | RAB9A (0.47) | BRAFMAPTCNR1MEN1KMT2A | |
| SCHEMBL2850258 | 0.89 | MAPT (0.51) | NPY5RBRAFMAPTMEN1KMT2A | |
| SCHEMBL2856867 | 0.88 | NPC1 (0.53) | NPY5RBRAFP2RY1MAPTGAA | |
| SCHEMBL2854572 | 0.87 | RAB9A (0.44) | BRAFMAPTMEN1KMT2AGAA | |
| SCHEMBL2854221 | 0.87 | MAPT (0.51) | P2RX1NPY5RMAPTMEN1KMT2A | |
| SCHEMBL2852565 | 0.87 | MAPT (0.42) | BRAFMAPTCNR1MEN1KMT2A | |
| SCHEMBL2853385 | 0.87 | MAPT (0.42) | BRAFMAPTMEN1KMT2AGAA | |
| SCHEMBL2853258 | 0.87 | NPY5R (0.45) | NPY5RMAPTCNR1MEN1KMT2A | |
| SCHEMBL2852360 | 0.87 | MAPT (0.42) | BRAFMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2848615 | 0.87 | MAPT (0.44) | NPY5RBRAFMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |