Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850258 | 0.92 | MAPT (0.51) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2854287 | 0.91 | MAPT (0.52) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2854572 | 0.90 | RAB9A (0.44) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2852565 | 0.90 | MAPT (0.42) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2852360 | 0.89 | MAPT (0.42) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2853258 | 0.89 | NPY5R (0.45) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2848615 | 0.89 | MAPT (0.44) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2853385 | 0.89 | MAPT (0.42) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2848317 | 0.89 | MAPT (0.46) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL2860939 | 0.88 | LMNA (0.45) | MAPTNPSR1MEN1KMT2ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |